Luxembourg researcher receives award for AFR PhD thesis on deep brain stimulation

Dr Andreas Husch, Postdoc at the LCSB at the University of Luxembourg, has been awarded the Best VPHi Thesis Award in In Silico Medicine with application in industrial R&D for his AFR PhD thesis, in which he presents innovative, image-based approaches to deep brain stimulation.

The award, sponsored by InSilicoTrials in collaboration with the VPH Institute, is awarded to individuals for outstanding achievements during their PhD thesis, specifically focusing on the translational aspects of their work, such as:

  • addressable market
  • product development phase that would benefit from the model/simulation
  • IP ownership
  • Patentability
  • industrial use readiness

Novel image-based computational approaches to deep brain stimulation

Deep brain stimulation (DBS) is an intervention based on implanting electrodes into the human brain to alleviate the symptoms of various diseases. Traditionally, DBS has been relying on image-guided approaches, applying the most recent imaging techniques available to guide surgery.

Computer scientist Dr Andreas Husch did his AFR PhD at the Centre Hospitalier de Luxembourg (CHL) and is now a Postdoc at the Luxembourg Centre for Systems Biomedicine (LCSB) at the University of Luxembourg

However, more than 60 years after the first experiments to stimulate areas in the deep brain with electrodes and more than 30 years after the first DBS treatments in the modern sense, still many open questions remain. A key problem in DBS research is the question of the precise definition of the optimal stimulation targets for the treatment of different diseases, particularly for Parkinson’s Disease.

In his AFR PhD project, carried out at the Centre Hospitalier de Luxembourg (CHL), in collaboration with the University of Luxembourg, the LCSB and Hochschule Trier, Dr Husch introduced novel image-based computational approaches to aid all clinical phases of deep brain stimulation: pre-operative planning, intra-operative navigation and post-operative care.

Prof Dr Rudi Balling, Director of the LCSB commented: “Andreas really deserves this price. He is just outstanding. It also shows nicely that the interdisciplinary cooperation between computer experts and medical doctors pays off.”

Find out more about this research project in our FNR Highlight ‘From flood prediction to deep brain stimulation’

About InSilicoTrials

InSilicoTrials is one of the industrial members of the Avicenna Alliance that works with Pharma and Medical Devices companies to create a secure cloud-based computational hub in an easy and cost effective way.

“I wish to thank both InSilicoTrials and the VPH Institute for this great opportunity. I am really honored to have received this prize! This will be also a special opportunity to investigate new ways to collaborate with the industry side of the community. InSilicoTrials’ approach of providing complex computational models as a compressive web service to scientists well aligns to our ideas of translational science bringing latest scientific results to the bedside respectively operating room. “ adds Dr Husch.

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